Prof. Dr. R.E. Bontrop
Theoretical Biology and Bioinformatics
Faculty of Science, Utrecht University
Kruytgebouw, room Z509
3584 CH Utrecht
Ronald Bontrop studied (Bio)chemistry at the University of Leiden. His PhD research -characterization of HLA class II molecules- was conducted at the Department of Immunohematology and Bloodbank of the University Hospital Leiden (Department head Prof. Dr. JJ van Rood). He received his PhD in 1987. At present Ronald Bontrop is director of the BPRC (www.bprc.nl) and spents one day per week in Utrecht.
Our current research interests deal with the comparative genetics of the immune systems of primates and their co-evolution with pathogens. Special emphasis is focussed on the genes of the Major Histocompatibility Complex (MHC) and Killer Cell Immunoglobulin-like receptors (KIR). Both of these gene families display copy number variation and abundant levels of allelic polymorphism. Susceptibility and resistance to a myriad of diseases is associated with the presence of particular MHC alleles.
For more information see also www.bprc.nl
For an up-to-date list of publications, please use this pubmed link.